Management of brain metastases: past, present, and future
Autor: | Routh A, Hickman Bt, Khansur T, Bass D |
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Rok vydání: | 1994 |
Předmět: |
Oncology
Adult Male medicine.medical_specialty Systemic disease Lung Neoplasms medicine.medical_treatment Breast Neoplasms Radiosurgery Dexamethasone Therapeutic goal Internal medicine Antineoplastic Combined Chemotherapy Protocols Medicine Humans Child Melanoma Aged Proportional Hazards Models Retrospective Studies Aged 80 and over Chemotherapy business.industry Brain Neoplasms Cancer General Medicine Middle Aged medicine.disease Survival Analysis Kidney Neoplasms Radiation therapy Neoplasms Unknown Primary Female Cranial Irradiation business Brain metastasis |
Zdroj: | Southern medical journal. 87(12) |
ISSN: | 0038-4348 |
Popis: | Brain metastasis is an important cause of morbidity and mortality in cancer patients. Because most of these patients die of systemic disease, the primary therapeutic goal is to improve the quality of life. Conventional therapy for brain metastases is usually whole-brain irradiation. Chemotherapy often results in regression of brain metastases in chemosensitive tumors. We review our institutional experience in the treatment of brain metastasis with both radiation and chemotherapy. In the future, improvement in the management of brain metastases will depend on improved chemotherapy, radiosensitizers, and radiotherapy techniques such as stereotactic radiosurgery. |
Databáze: | OpenAIRE |
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