Zinc and vitamin A deficiency in a cohort of children with autism spectrum disorder

Autor: Sinead M. O'Donnell, Tim Grant, Hilary Greaney, Annette Lalor, Deirdre U. Sweetman
Rok vydání: 2015
Předmět:
Vitamin
Male
Pediatrics
medicine.medical_specialty
Adolescent
Autism Spectrum Disorder
Population
behavioral disciplines and activities
Cohort Studies
03 medical and health sciences
chemistry.chemical_compound
0302 clinical medicine
030225 pediatrics
mental disorders
Developmental and Educational Psychology
medicine
Prevalence
Humans
0501 psychology and cognitive sciences
education
Child
Vitamin A
Normal range
education.field_of_study
business.industry
Vitamin A Deficiency
05 social sciences
Public Health
Environmental and Occupational Health
medicine.disease
Vitamin A deficiency
Zinc
chemistry
Autism spectrum disorder
Case-Control Studies
Child
Preschool
Pediatrics
Perinatology and Child Health
Cohort
Autism
Female
business
Child Nutritional Physiological Phenomena
Ireland
050104 developmental & child psychology
Blood sampling
Zdroj: Child: care, health and development. 45(3)
ISSN: 1365-2214
Popis: BACKGROUND AND OBJECTIVES Studies suggest that trace element and vitamin deficiencies are common in children with autism spectrum disorder (ASD). Data describing the rates of vitamin and trace element deficiencies in the ASD population of the northwest of Ireland is lacking. We wished to determine the prevalence of zinc and vitamin A deficiency in the ASD population compared with controls within this geographical area. METHODS Parents of children aged 2-18 years with ASD were invited to participate in the study. The control group consisted of well children attending the paediatric department for routine blood sampling. Children on vitamin supplements were excluded from both ASD and control groups. Informed written consent was obtained prior to recruitment. Samples were analysed for zinc and vitamin A levels according to standardized laboratory procedures. RESULTS Seventy-four of the 150 children with ASD who were invited and 72 controls underwent blood sampling. Mean zinc and vitamin A levels were normal in both groups. There were significantly more males in the ASD group (88% versus 56%, p value
Databáze: OpenAIRE
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