Necrotizing fasciitis in liver cirrhosis
| Autor: | Yu-San Lin, Kuo-Feng Huang, Tzong-Bor Sun, Chin-Choon Yeh, Haw-Yen Chiu, Cheng Liu, Min-Hsiang Hung, Shih-Feng Weng, Chun-Chia Chen |
|---|---|
| Jazyk: | angličtina |
| Předmět: |
Hepatitis
Univariate analysis medicine.medical_specialty Creatinine Cirrhosis biology business.industry necrotizing fasciitis Mortality rate liver cirrhosis Serum albumin hypoalbuminemia medicine.disease mortality Surgery chemistry.chemical_compound chemistry risk factor medicine biology.protein Hypoalbuminemia Fasciitis business |
| Zdroj: | Formosan Journal of Surgery. (4):132-137 |
| ISSN: | 1682-606X |
| DOI: | 10.1016/j.fjs.2014.07.001 |
| Popis: | SummaryBackgroundNecrotizing fasciitis (NF) is associated with a high mortality rate. Hepatitis is endemic in Taiwan, and liver cirrhosis is associated with the development of NF. The characteristics of these patients, however, have not been well documented or the predictors of mortality clearly identified. The purpose of this study is to identify predictors of mortality in patients with liver cirrhosis and necrotizing fasciitis.MethodsThis study was conducted at the Chi-Mei Medical Center in southern Taiwan. Demographic data, clinical characteristics, and the microorganisms responsible for NF in patients with liver cirrhosis were recorded. To identify independent predictors associated with mortality, univariate analysis followed by multivariate logistic regression modeling was performed.ResultsDuring the period 2003–2011, a total of 55 patients with liver cirrhosis and NF were treated at the Chi-Mei Medical Center. Most patients had infections by monomicrobial Gram-negative bacilli. Univariate analysis revealed that severity of liver cirrhosis, shock, band polymorphonuclear neutrophil (>10%), international normalized ratio (>1.5), serum creatinine (>2.0 mg/dL), serum albumin (60 seconds) were significantly associated with mortality. However, multivariate logistic regression analysis revealed that serum albumin of |
| Databáze: | OpenAIRE |
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