Tar, nicotine and carbon monoxide yield of UK cigarettes and the risk of non-muscle-invasive and muscle-invasive bladder cancer

Autor: Ranti Fayokun, D. Michael A. Wallace, Maurice P. Zeegers, Richard T. Bryan, Sylvia H J Jochems, Frederik J. van Schooten, Frits H.M. van Osch, Nicholas D. James, Charlotte G G M Pauwels, Kar Keung Cheng
Přispěvatelé: Promovendi NTM, Genetica & Celbiologie, RS: NUTRIM - R3 - Respiratory & Age-related Health, Farmacologie en Toxicologie, RS: CAPHRI - R5 - Optimising Patient Care, Complexe Genetica
Jazyk: angličtina
Rok vydání: 2019
Předmět:
Zdroj: European Journal of Cancer Prevention, 28(1), 40-44. LIPPINCOTT WILLIAMS & WILKINS
ISSN: 0959-8278
Popis: Cigarette smoking is a major risk factor for bladder cancer (BC); however, the impact of cigarette content remains unclear. This study aims to investigate tar, nicotine and carbon monoxide (TNCO) yields of different filtered cigarettes in relation to BC risk. From the Bladder Cancer Prognosis Programme 575 non-muscle-invasive bladder cancer (NMIBC) cases, 139 muscle-invasive bladder cancer (MIBC) cases and 130 BC-free controls with retrospective data on smoking behaviour and cigarette brand were identified. Independently measured TNCO yields of cigarettes sold in the UK were obtained through the UK Department of Health and merged with the Bladder Cancer Prognosis Programme dataset to estimate the daily intake of TNCO. BC risk increased by TNCO intake category for NMIBC cases (P
Databáze: OpenAIRE