Comparison of early-onset neonatal sepsis caused by Escherichia coli and group B Streptococcus

Autor: Madeline Tamayo, Alan I. Hartstein, Mary Jo O'Sullivan, Victor Hugo Gonzalez-Quintero, Kathleen Mayor-Lynn, Sonia Roger
Rok vydání: 2005
Předmět:
Zdroj: American Journal of Obstetrics and Gynecology. 192:1437-1439
ISSN: 0002-9378
DOI: 10.1016/j.ajog.2004.12.031
Popis: The purpose of this study was to compare maternal characteristics and neonatal morbidity and mortality rates that are associated with early-onset neonatal sepsis that is caused by group B Streptococcus and Escherichia coli.This was a retrospective review of newborn infants with a positive blood culture (and/or cerebrospinal fluid) that was positive for either E coli or group B Streptococcus during the first week of life. Data were abstracted from maternal and neonatal medical records.Among 28,659 deliveries during the study period, 102 episodes of early-onset neonatal sepsis were identified, 61 of which were caused by group B Streptococcus and 41 of which were caused by E coli. E coli sepsis cases had a lower birth weight, a higher percentage with 5-minute Apgar score7, and a longer stay in the hospital neonatal intensive care unit and required mechanical ventilation more frequently. Death after early-onset neonatal sepsis with E coli was also more frequent.Early-onset sepsis with E coli is associated with more morbidity and a higher mortality rate compared with early-onset group B Streptococcus.
Databáze: OpenAIRE