The differences in left ventricular torsional behavior between patients with hypertrophic cardiomyopathy and hypertensive heart disease
Autor: | Tomoaki Ohtsuka, Yuji Shigematsu, Go Hiasa, Hideki Okayama, Takumi Sumimoto, Jitsuo Higaki, Shinji Inaba, Akiyoshi Ogimoto, Junichi Funada, Makoto Saito, Katsuji Inoue, Kazuhisa Nishimura, Toyofumi Yoshii |
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Rok vydání: | 2011 |
Předmět: |
Male
Torsion Abnormality medicine.medical_specialty Heart Diseases Diastole Ventricular Dysfunction Left Internal medicine medicine Humans cardiovascular diseases Aged Ejection fraction business.industry Hypertrophic cardiomyopathy Torsion (mechanics) Cardiomyopathy Hypertrophic Middle Aged medicine.disease Control subjects Hypertensive heart disease Hypertension cardiovascular system Cardiology Early diastolic Female Hypertrophy Left Ventricular Cardiology and Cardiovascular Medicine business |
Zdroj: | International Journal of Cardiology. 150:301-306 |
ISSN: | 0167-5273 |
Popis: | Background The aim of this study was to investigate the differences in left ventricular (LV) twisting behavior between patients with hypertrophic cardiomyopathy (HCM) and hypertensive heart disease (HHD). Methods Forty-four patients with HCM (mean age, 63±15years), 35 patients with HHD (mean age, 63±13years) and 20 age and sex-matched control subjects were evaluated. After a standard echocardiographic examination, LV twist and twisting velocity profiles from apical and basal short-axis images were analyzed using two-dimensional speckle tracking imaging. Results LV diastolic and systolic dimensions, and ejection fraction were not significantly different among the groups. LV mass index and early diastolic mitral annular velocity were not significantly different between the HCM and HHD groups. The peak torsion in the HCM and HHD groups was significantly greater than that in the control group. The peak untwisting velocity in the HCM group was comparable with that in the control group. However, when the peak untwisting velocity was corrected by peak torsion, this ratio was significantly decreased in the HCM group compared with the values in the HHD and control groups. The time to peak untwisting velocity in the HCM group was significantly longer than the values in the HHD and control groups. Conclusions These results suggest that enhanced peak torsion in HCM may improve untwisting behavior, but this mechanism fails to fully compensate for impaired untwisting behavior compared with HHD. |
Databáze: | OpenAIRE |
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