Muscle CT scan findings in McLeod syndrome and chorea-acanthocytosis

Autor: Shozo Ishikawa, Shu-ichi Ikeda, Norinao Hanyu, Naoko Tachibana, Rho-Ichi Hayashi, Ken-Ichi Tabata, Junko Takahashi, Naoharu Fujimori
Rok vydání: 2000
Předmět:
Zdroj: Muscle & Nerve. 23:1113-1116
ISSN: 1097-4598
0148-639X
DOI: 10.1002/1097-4598(200007)23:7<1113::aid-mus15>3.0.co;2-6
Popis: Computed tomography (CT) scans of lower leg muscles reveal a selective pattern of fat infiltration in the posterior compartment with spared gracilis, semitendinosus, and the lateral head of the gastrocnemius in both McLeod syndrome and chorea-acanthocytosis, which are disorders characterized by the presence of circulating acanthocytes. The selectivity of affected muscles indicates that late onset and slowly progressive muscular atrophy in both diseases could be a consequence of primary myopathy. Asymmetrical muscle involvement may be seen during the process of degeneration only in McLeod syndrome, however, and may be helpful in distinguishing this disease from chorea-acanthocytosis.
Databáze: OpenAIRE