Structural and electrochemical studies of functionalization of reduced graphene oxide with alkoxyphenylporphyrin mono- and tetra- carboxylic acid: application to DNA sensors
| Autor: | Hélène Sauriat-Dorizon, Zouhour Hsine, Hafsa Korri-Youssoufi, Yaqiong Wang, Rym Mlika |
|---|---|
| Přispěvatelé: | Institut de Chimie Moléculaire et des Matériaux d'Orsay (ICMMO), Institut de Chimie du CNRS (INC)-Université Paris-Saclay-Centre National de la Recherche Scientifique (CNRS), Université de Monastir - University of Monastir (UM) |
| Jazyk: | angličtina |
| Rok vydání: | 2020 |
| Předmět: |
Materials science
General Chemical Engineering 02 engineering and technology Inner sphere electron transfer 010402 general chemistry 01 natural sciences Nanomaterials law.invention law Electrochemistry Reduced graphene oxide [SDV.BBM.BC]Life Sciences [q-bio]/Biochemistry Molecular Biology/Biochemistry [q-bio.BM] Nanocomposite Graphene DNA [CHIM.MATE]Chemical Sciences/Material chemistry 021001 nanoscience & nanotechnology Nanomaterial 0104 chemical sciences Dielectric spectroscopy Chemical engineering Outer sphere electron transfer Cyclic voltammetry 0210 nano-technology Biosensor Tetraphenylporphyrin |
| Zdroj: | Electrochimica Acta Electrochimica Acta, Elsevier, 2020, 357, pp.136852. ⟨10.1016/j.electacta.2020.136852⟩ |
| ISSN: | 0013-4686 |
| DOI: | 10.1016/j.electacta.2020.136852⟩ |
| Popis: | International audience; Blend of graphene and π-conjugated molecules presents a new class of material with unique mechanical, optical, and electrical properties. Here, we study the physico-chemical and electrical properties of nanomaterials that combine chemical reduced graphene oxide (CRGO) features and functionalities of tetra-butyloxyphenylporphyrins bearing a mono- or tetra-carboxylic groups. The hybrid nanomaterials are characterized by different techniques including UV-visible, FT-IR, Raman spectroscopy, MEB and SEM. Their electrochemical properties are studied by cyclic voltammetry (CV) with inner sphere and outer sphere redox markers as well as the electrochemical impedance spectroscopy (EIS). Our results support the formation of strong interactions between porphyrins and CRGO. Furthermore, we investigated the relationship between structure and electronic properties of porphyrins on the resulting blend. We demonstrated that these modified porphyrins with alkoxy and carboxyl groups not only improve the dispersion of CRGO, but also enhances the electron transfer ability. These nanocomposites open up new opportunities for the fabrication of biosensors devices. The detection of DNA demonstrated with LOD down to attomolar range and with ability to discriminate between DNA from Rpob gene of M. Tuberculosis strand and mutated in PCR sample. |
| Databáze: | OpenAIRE |
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