Genome Recombination between the Delta and Alpha Variants of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2)

Autor:	Tsuyoshi, Sekizuka, Kentaro, Itokawa, Masumichi, Saito, Michitsugu, Shimatani, Shutoku, Matsuyama, Hideki, Hasegawa, Tomoya, Saito, Makoto, Kuroda
Rok vydání:	2022
Předmět:	Recombination Genetic Microbiology (medical) Infectious Diseases Japan SARS-CoV-2 COVID-19 Humans General Medicine
Zdroj:	Japanese Journal of Infectious Diseases. 75:415-418
ISSN:	1884-2836 1344-6304
DOI:	10.7883/yoken.jjid.2021.844
Popis:	Prominent genomic recombination has been observed between the Delta and Alpha variants of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), isolated from clinical specimens in Japan. Interestingly, the recombination variant detected in this study carries a spike protein identical to that in the domestic Delta variant, thereby suggesting that further risks would not be associated with infectivity and immune escape. The recombinant was classified as an XC lineage in the PANGOLIN database. It is necessary to intensively study such marked genetic variations and characterize emerging variants after careful verification of their lineage and clade assignment.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::06bd489c8bccbdd7ed795ac26ed9de27 https://doi.org/10.7883/yoken.jjid.2021.844 Zobrazit plný text záznamu