Effects of a mixed exercise program on cancer related-fatigue and health-related quality of life in oncogeriatric patients: A feasibility study
| Autor: | Riesco Eléonor, Pavic Michel, Fontvieille Adeline, Parent-Roberge Hugo, Maréchal René, Fülöp Tàmàs |
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| Rok vydání: | 2020 |
| Předmět: |
medicine.medical_specialty
Population Context (language use) 03 medical and health sciences Grip strength 0302 clinical medicine Quality of life Neoplasms medicine Aerobic exercise Humans 030212 general & internal medicine education Cancer-related fatigue Exercise Fatigue Aged education.field_of_study business.industry Cancer medicine.disease Exercise Therapy Oncology Geriatric oncology 030220 oncology & carcinogenesis Physical therapy Quality of Life Feasibility Studies Geriatrics and Gerontology medicine.symptom business |
| Zdroj: | Journal of geriatric oncology. 12(6) |
| ISSN: | 1879-4076 |
| Popis: | Objectives Cancer-related fatigue (CRF) is the most debilitating side effect occurring with cancer treatment accumulation. Although combining aerobic and resistance exercise is an effective strategy to counteract this side effect, there is a paucity of studies performed with older patients even if this is the most affected population. Hence, the objective was to assess the feasibility and the impact of a twelve-week exercise program performed during cancer treatment on CRF, quality of life, and physical capacity in older adults diagnosed with early-stage cancer. Material and Methods Twenty patients with cancer (70 ± 4 years) beginning systemic cancer treatments were recruited and randomized into two groups: 1) aerobic and resistance training (MIX) and 2) stretching (CON). Both groups were supervised three times/week for a total of twelve weeks. The primary outcome was feasibility and secondary outcomes were CRF (FACIT-Fatigue questionnaire), health-related quality of life (HRQoL) (EORTC QLQ-C30 questionnaire) and physical capacity (6MWT and grip strength). Results In Mix, both exercise adherence (88.2%) and completion rate (86.6%) were high, which suggests that exercise is feasible in an oncologic context. In the MIX group, HRQoL improved (p = 0.05) and CRF was clinically, ableit non-significantly (p = 0.09), decreased. Concerning physical capacity, MIX showed a clinical improvement in the 6MWT during the intervention (p = 0.002) compared to CON. Conclusion This study suggests that, in older patients with cancer undergoing adjuvant or neoadjuvant systemic treatments, a mixed exercise program is feasible, well tolerated and might help mitigate CRF and HRQoL decrements. |
| Databáze: | OpenAIRE |
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