Counterion effects in the catalytic stereoselective synthesis of 2,3'-pyrrolidinyl spirooxindoles
| Autor: | John D. Schreiber, Jacob P. MacDonald, Annaliese K. Franz, Benjamin H. Shupe |
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| Rok vydání: | 2013 |
| Předmět: |
chemistry.chemical_classification
Annulation Indoles Molecular Structure Metal salts Metals and Alloys Stereoisomerism General Chemistry Silanes Catalysis Pyrrolidinones Surfaces Coatings and Films Electronic Optical and Magnetic Materials Stereocenter Oxindoles chemistry Materials Chemistry Ceramics and Composites Organic chemistry Stereoselectivity Reactivity (chemistry) Spiro Compounds Counterion Lewis Acids |
| Zdroj: | Chemical communications (Cambridge, England). 50(40) |
| ISSN: | 1364-548X |
| Popis: | A Lewis acid-catalyzed stereoselective [3+2] annulation of crotylsilanes with iminooxindoles is reported to access 2,3′-pyrrolidinyl spirooxindoles with four stereocenters. The addition of NaBArF significantly enhances reactivity, allowing either metal salts or acidic clay to be effective catalysts for the stereoselective reaction. |
| Databáze: | OpenAIRE |
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