Cerebral arterial spasm
| Autor: | Shelley N. Chou, George S. Allen, Lyle A. French, Lawrence H. A. Gold |
|---|---|
| Rok vydání: | 1974 |
| Předmět: |
Male
Phenoxybenzamine medicine.diagnostic_test business.industry Subarachnoid Hemorrhage Cerebral Angiography body regions Disease Models Animal stomatognathic diseases Dogs Ischemic Attack Transient In vivo Basilar Artery Anesthesia Animals Medicine Female Serotonin Antagonists Serotonin business Cerebral arterial spasm Cerebral angiography medicine.drug |
| Zdroj: | Journal of Neurosurgery. 40:451-458 |
| ISSN: | 0022-3085 |
| Popis: | ✓ In vivo experiments in dogs demonstrated that physiological concentrations of serotonin, when injected intracisternally, caused cerebral arterial spasm that lasted for at least 3 hours. Comparable spasm was produced by the injection of blood containing approximately the same amount of serotonin. Phenoxybenzamine reversed both the spasm produced by pure serotonin and that produced by blood. A hypothesis of the etiology of cerebral arterial spasm is proposed based on the experimental results of the entire study. |
| Databáze: | OpenAIRE |
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