Exploring the Relationship Between Movement Disorders and Physical Activity in Patients With Schizophrenia: An Actigraphy Study
| Autor: | Peter N. van Harten, Jasper van Oort, Jeroen Deenik, Lydia E Pieters, Diederik E. Tenback |
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| Přispěvatelé: | RS: MHeNs - R2 - Mental Health, Psychiatrie & Neuropsychologie |
| Rok vydání: | 2021 |
| Předmět: |
Male
Movement disorders Stress-related disorders Donders Center for Medical Neuroscience [Radboudumc 13] Akathisia 0302 clinical medicine Extrapyramidal symptoms QUALITY-OF-LIFE 130 000 Cognitive Neurology & Memory Medicine psychosis parkinsonism Dystonia Movement Disorders Parkinsonism SEVERE MENTAL-ILLNESS SEDENTARY BEHAVIOR parkins onism ASSOCIATION Middle Aged Psychiatry and Mental health NEGATIVE SYNDROME SCALE REMISSION CRITERIA Schizophrenia MOTOR ABNORMALITIES RELIABILITY Female medicine.symptom Adult Psychosis medicine.medical_specialty AcademicSubjects/MED00810 03 medical and health sciences sedentary All institutes and research themes of the Radboud University Medical Center Internal medicine Humans Exercise Aged somatic health ANTIPSYCHOTIC-NAIVE PATIENTS business.industry behavior medicine.disease Actigraphy 030227 psychiatry extrapyramidal symptoms HIGH-RISK Dyskinesia business 030217 neurology & neurosurgery Regular Articles |
| Zdroj: | Schizophrenia Bulletin, 47, 4, pp. 906-914 Schizophrenia Bulletin Schizophrenia Bulletin, 47, 906-914 Schizophrenia Bulletin, 47(4), 906-914. Oxford University Press |
| ISSN: | 0586-7614 |
| Popis: | Low physical activity (PA) and sedentary behavior (SB) are major contributors to mental health burden and increased somatic comorbidity and mortality in people with schizophrenia and related psychoses. Movement disorders are highly prevalent in schizophrenia populations and are related to impaired functioning and poor clinical outcome. However, the relationship between movement disorders and PA and SB has remained largely unexplored. Therefore, we aimed to examine the relationship between movement disorders (akathisia, dyskinesia, dystonia, and parkinsonism) and PA and SB in 216 patients with schizophrenia and related psychoses. Actigraphy, the St. Hans Rating Scale for extrapyramidal syndromes, and psychopathological ratings (PANSS-r) were applied. Data were analyzed using multiple linear regression, adjusting for sex, age, negative symptoms, and defined daily dose of prescribed antipsychotics. Parkinsonism was significantly associated with decreased PA (β = −0.21, P < .01) and increased SB (β = 0.26, P < .001). For dystonia, only the relationship with SB was significant (β = 0.15, P < .05). Akathisia was associated with more PA (β = 0.14, P < .05) and less SB (β = −0.15, P < .05). For dyskinesia, the relationships were non-significant. In a prediction model, akathisia, dystonia, parkinsonism and age significantly predicted PA (F(5,209) = 16.6, P < .001, R2Adjusted = 0.27) and SB (F(4,210) = 13.4, P < .001, R2Adjusted = 0.19). These findings suggest that movement disorders, in particular parkinsonism, are associated with reduced PA and increased SB in patients with psychotic disorders. Future studies should take movement disorders into account when examining PA and SB, to establish the clinical value of movement disorders in activating people with psychotic disorders to improve their mental and somatic health. |
| Databáze: | OpenAIRE |
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