Mucormycosis in a Non-Hodgkin Lymphoma Patient Caused by Syncephalastrum racemosum: Case Report and Review of Literature
| Autor: | Juan Xicohtencatl-Cortes, Roberto Arenas, Georgina Rodríguez-Gutiérrez, Sonia Toussaint, Adrián A. Schcolnik-Cabrera, Jorge García-Méndez, Erika M. Carrillo-Casas, Mónica E. Moreno-Morales, Rigoberto Hernández-Castro |
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| Rok vydání: | 2015 |
| Předmět: |
Adult
Pathology medicine.medical_specialty Antifungal Agents Veterinary (miscellaneous) Fulminant Applied Microbiology and Biotechnology Microbiology Immunocompromised Host chemistry.chemical_compound Amphotericin B medicine Humans Mucormycosis Microscopy Lung Diseases Fungal biology Histocytochemistry business.industry Lymphoma Non-Hodgkin medicine.disease biology.organism_classification Dermatology Peripheral stem cell transplantation Pneumonia Debridement chemistry Mucorales Female Zygomycosis Caspofungin business Agronomy and Crop Science Syncephalastrum racemosum medicine.drug |
| Zdroj: | Mycopathologia. 180:89-93 |
| ISSN: | 1573-0832 0301-486X |
| DOI: | 10.1007/s11046-015-9878-1 |
| Popis: | Mucormycosis is a rare opportunistic fungal infection caused by saprophytic zygomycetes. These fungal infections are caused by members of the mucorales. The clinical importance of zygomycosis, an emerging and frequently fatal mycotic disease, has increased during recent years, due to several risk factors such as (a) the use of broad-spectrum antibiotic, (b) use of empirical antifungal treatment (mainly triazoles), and (c) aggressive chemotherapy and sustained leucopenia (i.e., peripheral stem cell transplantation). An almost fulminant pneumonia caused by Syncephalastrum racemosum in an immunocompromised patient with an aggressive non-Hodgkin lymphoma (NHL) is described. Despite treatment with amphotericin B, deoxycholate, caspofungin, and surgical resection of fungal bodies from both lungs, and survival of 10 months without relapsing from fungal infection, the patient died due to hematological complications from an unresponsive disease. Herein is the description of the first case of pulmonary infection caused by Syncephalastrum racemosum. |
| Databáze: | OpenAIRE |
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