Exposure Assessment in the National Children’s Study: Introduction
| Autor: | Richard Y. Wang, Maria Morandi, L-J. Sally Liu, Asa Bradman, Tina Bahadori, Mary Kay O'Rourke, Dana B. Barr, Kent Thomas, Halûk Özkaynak, P. Barry Ryan, Valerie Zartarian, Robin M. Whyatt, Larry L. Needham, James J. Quackenboss, Roy C. Fortmann, Gerry G. Akland, Luke P. Naeher |
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| Rok vydání: | 2005 |
| Předmět: |
Adult
Male Adolescent exposure assessment Health Toxicology and Mutagenesis media_common.quotation_subject MEDLINE Child Welfare Pregnancy Surveys and Questionnaires Environmental health Environmental monitoring environmental monitoring questionnaire National Children's Study Humans Medicine Quality (business) Organic Chemicals United States Environmental Protection Agency Child Mini-Monograph media_common Exposure assessment Estimation limit of detection business.industry Research Infant Newborn Public Health Environmental and Occupational Health Infant Environmental Exposure Environmental exposure Allergens National Children’s Study United States Epidemiologic Studies National Institutes of Health (U.S.) Inorganic Chemicals Maternal Exposure Child Preschool biomonitoring Environmental Pollutants Female Centers for Disease Control and Prevention U.S business Quality assurance Environmental Monitoring |
| Zdroj: | Environmental Health Perspectives |
| ISSN: | 1552-9924 0091-6765 |
| DOI: | 10.1289/ehp.7613 |
| Popis: | The science of exposure assessment is relatively new and evolving rapidly with the advancement of sophisticated methods for specific measurements at the picogram per gram level or lower in a variety of environmental and biologic matrices. Without this measurement capability, environmental health studies rely on questionnaires or other indirect means as the primary method to assess individual exposures. Although we use indirect methods, they are seldom used as stand-alone tools. Analyses of environmental and biologic samples have allowed us to get more precise data on exposure pathways, from sources to concentrations, to routes, to exposure, to doses. They also often allow a better estimation of the absorbed dose and its relation to potential adverse health outcomes in individuals and in populations. Here, we make note of various environmental agents and how best to assess exposure to them in the National Children's Study--a longitudinal epidemiologic study of children's health. Criteria for the analytical method of choice are discussed with particular emphasis on the need for long-term quality control and quality assurance measures. |
| Databáze: | OpenAIRE |
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