Regional lung ventilation in humans during hypergravity studied with quantitative SPECT
| Autor: | Johan Petersson, Dag Linnarsson, Alejandro Sanchez-Crespo, Margareta Mure, Sten G. E. Lindahl, Lars L. Karlsson, Malin Ax |
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| Rok vydání: | 2013 |
| Předmět: |
Adult
Male Pulmonary and Respiratory Medicine Supine position Physiology Ventilation perfusion mismatch Hypergravity Single-photon emission computed tomography Young Adult Psychophysics Humans Medicine Lung Tomography Emission-Computed Single-Photon medicine.diagnostic_test business.industry General Neuroscience Blood flow Perfusion medicine.anatomical_structure Anesthesia Breathing Female Pulmonary Ventilation business |
| Zdroj: | Respiratory Physiology & Neurobiology. 189:558-564 |
| ISSN: | 1569-9048 |
| DOI: | 10.1016/j.resp.2013.08.007 |
| Popis: | Recently we challenged the view that arterial desaturation during hypergravity is caused by redistribution of blood flow to dependent lung regions by demonstrating a paradoxical redistribution of blood flow towards non-dependent regions. We have now quantified regional ventilation in 10 healthy supine volunteers at normal and three times normal gravity (1G and 3G). Regional ventilation was measured with Technegas ((99m)Tc) and quantitative single photon emission computed tomography (SPECT). Hypergravity caused arterial desaturation, mean decrease 8%, p |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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