Doppler Ultrasound of Hepatic Blood Flow for Noninvasive Evaluation of Liver Fibrosis Compared with Liver Biopsy and Transient Elastography
| Autor: | J. J. W. Tischendorf, Nikolaus Gassler, Christian Trautwein, Holger H. Lutz, F. W. Tischendorf |
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| Rok vydání: | 2012 |
| Předmět: |
Adult
Liver Cirrhosis Male medicine.medical_specialty Physiology Biopsy Chronic liver disease Gastroenterology Hepatitis Fibrosis Internal medicine medicine Humans Prospective Studies Aged Cholestasis medicine.diagnostic_test Portal Vein business.industry Ultrasonography Doppler Middle Aged Hepatology medicine.disease Fatty Liver Liver ROC Curve Liver biopsy Elasticity Imaging Techniques Female Vascular Resistance Radiology Steatosis Transient elastography business Liver Circulation |
| Zdroj: | Digestive Diseases and Sciences. 57:2222-2230 |
| ISSN: | 1573-2568 0163-2116 |
| DOI: | 10.1007/s10620-012-2153-0 |
| Popis: | Accurate quantification of liver fibrosis is essential for therapeutic decision-making and follow-up of chronic liver diseases. To optimize the quality of non-invasive assessment of liver fibrosis in patients with chronic hepatopathy we compared Doppler ultrasound with liver histology and transient elastography (TE). In this prospective observational study, we performed Doppler ultrasound of hepatic blood vessels as well as TE in 125 patients who underwent liver biopsy for diagnostic work-up of hepatopathy. Hepatic venous flow was evaluated by determining resistance index (HVRI) of the right hepatic vein. Doppler and TE results were compared with histological staging, grading and degree of steatosis obtained by liver biopsy. HVRI showed a high reliability in predicting fibrosis stage FII or higher (AUROC 93.7 %, HVRI |
| Databáze: | OpenAIRE |
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