The Tego™ needleless connector for hemodialysis catheters may protect against catheter colonization
Autor: | M. J. Pérez-Granda, María Guembe, Luis Alcalá, Emilio Bouza, Raquel Cruces |
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Rok vydání: | 2016 |
Předmět: |
Microbiology (medical)
medicine.medical_specialty Hemodialysis Catheter Kaplan-Meier Estimate 030501 epidemiology Models Biological In vitro model 03 medical and health sciences 0302 clinical medicine Renal Dialysis medicine Humans 030212 general & internal medicine Needleless connector business.industry General Medicine Contamination Cannula Surgery Catheter Infectious Diseases Blood Culture Blood culture bottles Catheter-Related Infections Aseptic processing 0305 other medical science business Vascular Access Devices |
Zdroj: | European Journal of Clinical Microbiology & Infectious Diseases. 35:1341-1345 |
ISSN: | 1435-4373 0934-9723 |
DOI: | 10.1007/s10096-016-2670-4 |
Popis: | Catheter connectors used in hemodialysis patients are those with open caps to manage high blood flows. However, current guidelines for the prevention of catheter infections recommend closed connectors. Tego™ is a closed connector designed to enable high blood flows. We used an in vitro model to compare the efficacy of Tego™ against contamination with that of standard caps in a real-life practice scenario. The model consisted of 200 blood culture bottles (BCB) with an inserted cannula closed either with Tego™ (100) or with open caps (100). BCB were manipulated using two different methods: under aseptic conditions and with gloves contaminated with a 0.05 McFarland Staphylococcus aureus solution. The BCB were incubated at 37 °C under continuous shaking for up to 7 days or until positive. When a BCB turned positive, 100 μL of the fluid was cultured. The positivity rate and time to positivity of the BCB in each method were compared. Overall, 4.0 % of BCB with Tego™ and 52.0 % of BCB with open caps were positive in the sterile model (p |
Databáze: | OpenAIRE |
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