Effect of oestrogen on pregnancy of guinea-pigs
Autor: | Iris L. Sin, Anne Y. Merrick, P. R. Kelleher, John J. Evans |
---|---|
Rok vydání: | 1981 |
Předmět: |
endocrine system
Embryology Time Factors Litter Size Pregnancy animal Guinea Pigs Physiology Endocrinology Corpus Luteum Pregnancy Medicine Animals reproductive and urinary physiology Normal range Progesterone Estradiol urogenital system business.industry Obstetrics and Gynecology Histology Cell Biology medicine.disease medicine.anatomical_structure Reproductive Medicine Gestation Pregnancy Animal Female business Corpus luteum |
Zdroj: | Journal of reproduction and fertility. 62(1) |
ISSN: | 0022-4251 |
Popis: | Pregnant guinea-pigs were injected with oestrogen at different stages of gestation. After injections on Days 17 and 18 and on Days 25, 26, 32 and 33 peripheral maternal progesterone concentrations were lower than in control animals. Histology showed deleterious changes in the corpora lutea. After injections on Days 10 and 11 the maternal progesterone concentrations remained in the normal range for some time in 12 of 16 guinea-pigs and the corpora lutea appeared histologically normal. Oestrogen therefore affects the pregnancy differently at different stages of gestation. |
Databáze: | OpenAIRE |
Externí odkaz: |