The level of allergens in dust samples collected from selected schools in Shiraz, Iran and its asthma-risk implications
| Autor: | Mohammad Fereidouni, Mozhgan Moghtaderi, Shirin Farjadian, Saeed Hosseini Teshnizi, Mohammad Ali Ashraf, Hesamodin Nabavizadeh |
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| Rok vydání: | 2020 |
| Předmět: |
Male
Pulmonary and Respiratory Medicine Adolescent education Immunology Cockroaches Iran medicine.disease_cause complex mixtures Arthropod Proteins Mice Allergen immune system diseases biology.animal Environmental health Mite Animals Humans Immunology and Allergy Medicine Antigens Dermatophagoides Child Asthma Inhalation Exposure Cockroach Schools biology business.industry Dust General Medicine Allergens Dust mites biology.organism_classification medicine.disease respiratory tract diseases Cysteine Endopeptidases Air Pollution Indoor Cats Female Cat allergen business |
| Zdroj: | Allergologia et Immunopathologia. 48:90-94 |
| ISSN: | 0301-0546 |
| DOI: | 10.1016/j.aller.2019.05.005 |
| Popis: | Background Both home and school are important places where children are exposed to various indoor allergens. This study aimed to identify the profile of indoor allergens in schools and its impact on asthma development. Methods A total of 104 classrooms from 52 schools were selected for dust collection during the fall of 2017. The levels of indoor allergens including dust mite (Der f1, Der p1), cat (Fel d1), cockroach (Bla g1) and mouse (Mus m1) were measured by enzyme linked immunosorbent assay (ELISA). The diagnosis of asthma was made in all students of the selected classes by the allergist. The collected data were analyzed using SPSS version 21.0. Results Out of 2816 students in the selected classes, 180 students were involved with asthma. Students were mostly exposed to Bla g1 (83.1%), followed by Der f1 (51.5%), Mus m 1 (45.5%), Der p1 (8.9%) and Fel d1 (7.9%) in the dust collected from 101 classrooms. Although levels of all studied allergens in the settled dust of the classrooms were low, there was a relationship between Fel d1 in the classroom dust and development of asthma. Conclusion This study showed considerable levels of cockroach allergens in schools. Exposure to cat allergen in our schools played an important role in asthma development; further school-based investigations require evaluating the role of classroom allergen on asthma development. |
| Databáze: | OpenAIRE |
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