Rapid Quantitative Chairside Test for Active MMP-8 in Gingival Crevicular Fluid: First Clinical Data
| Autor: | S. K. Munjal, Timo Sorsa, F. Struck, C.-D Bauermeister, L. Netuschil, N. Prescher, Kurt Maier |
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| Rok vydání: | 2007 |
| Předmět: |
Immunoassay
Periodontitis Time Factors Periodontist business.industry Point-of-Care Systems General Neuroscience Dentistry Pilot Projects Gingival Crevicular Fluid 030206 dentistry medicine.disease General Biochemistry Genetics and Molecular Biology 3. Good health Crevicular fluid 03 medical and health sciences Matrix Metalloproteinase 8 0302 clinical medicine Dental Offices History and Philosophy of Science 030220 oncology & carcinogenesis medicine Humans business |
| Zdroj: | Annals of the New York Academy of Sciences. 1098:493-495 |
| ISSN: | 0077-8923 |
| Popis: | In a first pilot field study 64 gingival crevicular fluid (GCF) samples were collected from patients of dental practitioners. The dentists (one orthodontist one periodontist, and one general practitioner) were asked to monitor the respective clinical status of the sites of sampling and to collect, if possible, sulcus fluid samples from healthy as well as af- fected sites from the same patient. The concentration of activated matrix metalloproteinase-8 (aMMP-8) in the GCF was recorded using a set of monoclonal antibodies and a novel DentoAnalyzer. From all three dental offices the distribution of the aMMP-8 values in GCF showed a congru- ent pattern, where healthy and periodontitis-affected inflamed sites were clearly disparate. |
| Databáze: | OpenAIRE |
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