The Characteristics of Iodine Nutrition Status in China After 20 Years of Universal Salt Iodization: An Epidemiology Study Covering 31 Provinces

Autor: Yanbo Li, Jin-an Zhang, Libin Liu, Nanwei Tong, Jianling Du, Guixia Wang, Zhongyan Shan, Jing Yang, Li Yan, Bingyin Shi, Chao Liu, Xiaochun Teng, Yongli Yao, Zhen Ye, Di Teng, Yongze Li, Qiao Zhang, Mei Zhu, Weiping Teng, Youmin Wang, Lanjie He, Xulei Tang, Lihui Zhang, Xiaoyang Lai, Xiaoguang Shi, Lihui Yang, Hui Sun, Jianming Ba, Er-Yuan Liao, Huibiao Quan, Guijun Qin, Yingfen Qin, Jun Zhu, Yuanming Xue, Bing Chen, Haiyi Chi, Liu Tingting
Rok vydání: 2021
Předmět:
Zdroj: Thyroid. 31:1858-1867
ISSN: 1557-9077
1050-7256
Popis: Background: Despite the implementation of the universal salt iodization (USI) program for correction of iodine deficiency in China for ∼20 years, the actual iodine nutrition status of Chinese residents and the prevalence of iodine deficiency and iodine excess are issues that need to be addressed. This nationally representative cross-sectional study was conducted across all 31 provinces of mainland China to gather extensive data on iodine nutrition status and the influential factors. Methods: This study included 78,470 participants, aged 18 years or older, who were interviewed and asked to answer a questionnaire. Urine iodine concentration (UIC) was measured by the inductively coupled plasma mass spectrometry method, and goiter was examined by thyroid ultrasonography. In addition, sixty 9-11 years old school children in each province were randomly selected to evaluate the UIC and thyroid ultrasonography. The iodine nutrition status was determined according to the World Health Organization guidelines. Results: The iodized salt coverage was 95.37%. The median urine iodine (MUI) was 177.89 μg/L (interquartile range [IQR], 117.89-263.90 μg/L) and goiter prevalence was 1.17% (confidence interval [95% CI 0.95-1.43]) in the adult population. The MUI was 199.75 μg/L (IQR, 128.41-303.37 μg/L) in school-age children, and goiter prevalence was 3.50% [95% CI, 2.93-4.13]. The percentage of individuals with UIC
Databáze: OpenAIRE