Drugs influencing acid base balance and bicarbonate concentration readings
| Autor: | Patrick Levy, Carole Schwebel, Renaud Tamisier, Marie Joyeux-Faure, Anne-Laure Borel, Jean-Louis Pépin, Ingrid Jullian-Desayes, Jean-Christian Borel, Fabrice Guerber |
|---|---|
| Rok vydání: | 2018 |
| Předmět: |
Obesity hypoventilation syndrome
medicine.medical_specialty business.industry Endocrinology Diabetes and Metabolism Bicarbonate High mortality Acid–base homeostasis Chronic hypoventilation medicine.disease Gastroenterology 03 medical and health sciences chemistry.chemical_compound 0302 clinical medicine Endocrinology 030228 respiratory system chemistry Internal medicine medicine 030212 general & internal medicine business Serum bicarbonate |
| Zdroj: | Expert review of endocrinologymetabolism. 11(2) |
| ISSN: | 1744-8417 |
| Popis: | Serum bicarbonate dosage is sensitive to pharmacological interferences. However, elevated bicarbonate concentration reflects chronic hypoventilation and has been proposed as a simple marker for screening patients with Obesity Hypoventilation Syndrome (OHS), a currently underdiagnosed multimorbid and high mortality disease. We provide a practical overview of the different drugs acting on the acid-base equilibrium to aid clinicians to interpret bicarbonate concentration readings. Little is known about the chronic impact of the usual doses of these drugs on serum bicarbonate concentration and further studies are needed. It is essential to take into account drugs that could interfere with this parameter to avoid misinterpretation of serum bicarbonate levels. |
| Databáze: | OpenAIRE |
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