Changes in quality of life over time-Dutch haemodialysis patients and general population compared

Autor: Mazairac, A.H., Wit, G.A. de, Penne, E.L., Weerd, N.C. van der, Jong, B. de, Grooteman, M.P.C., Dorpel, M.A. van den, Buskens, E., Dekker, F.W., Nube, M.J., Wee, P.M. ter, Boeschoten, E.W., Bots, M.L., Blankestijn, P.J., Hamersvelt, H.W. van
Přispěvatelé: Science in Healthy Ageing & healthcaRE (SHARE), Methods in Medicines evaluation & Outcomes research (M2O), Nephrology, Internal medicine, ICaR - Ischemia and repair
Jazyk: angličtina
Rok vydání: 2011
Předmět:
Zdroj: Nephrology Dialysis Transplantation, 26(6), 1984-1989. Oxford University Press
Nephrology, Dialysis, Transplantation, 26, 6, pp. 1984-9
Nephrology, Dialysis, Transplantation, 26, 1984-9
Nephrology, dialysis, transplantation, 26(6), 1984-1989. Oxford University Press
Nephrology, Dialysis, Transplantation, 26(6), 1984-1989. Oxford University Press
Mazairac, A H A, de Wit, G A, Penne, E L, van der Weerd, N C, Meyboom-De Jong, B, Grooteman, M P C, van den Dorpel, M A, Buskens, E, Dekker, F W, Nube, M J, ter Wee, P M, Boeschoten, E W, Bots, M L & Blankestijn, P J 2011, ' Changes in quality of life over time-Dutch haemodialysis patients and general population compared ', Nephrology, Dialysis, Transplantation, vol. 26, no. 6, pp. 1984-1989 . https://doi.org/10.1093/ndt/gfq680
ISSN: 1460-2385
0931-0509
DOI: 10.1093/ndt/gfq680
Popis: Item does not contain fulltext BACKGROUND: Improving the health-related quality of life (HRQOL) for haemodialysis patients is a considerable challenge. The aim of the present study was to compare changes in HRQOL in haemodialysis patients with those observed in the general population over a 10-year period and explore factors that might explain possible differences. METHODS: We compared 126 haemodialysis patients assessed in 1995 in the Netherlands Cooperative Study on the Adequacy of Dialysis-1 (NECOSAD-I) with 515 patients enrolled in 2006 in the ongoing Convective Transport Study (CONTRAST). Changes in HRQOL in these cohorts were compared with two representative samples from the general Dutch population, assessed in 1992 (n = 1,063) and 2001 (n = 10,600). HRQOL was measured with the SF-36 questionnaire. Differences in HRQOL were analysed with ANCOVA to adjust for demographic variables. To assess possible differences, we used multivariable regression analysis. RESULTS: HRQOL in haemodialysis patients in 2006 [CONTRAST, mean age 63 +/- 14 years (SD), 62% male] was significantly better than in 1995 (NECOSAD-I, 59 +/- 16 years, 53% male) in four domains of the SF-36: bodily pain (+ 5 points, P = 0.009), vitality (+ 7, P < 0.001), role-emotional (+ 14, P < 0.001) and mental health (+ 8, P < 0.001), after adjusting for demographic variables. This increment could partly be explained by improved haemoglobin and phosphate levels. Compared to the general population, HRQOL improvement was most outspoken in two domains: bodily pain (+ 6, P = 0.01) and role-emotional (+ 8, P = 0.007). CONCLUSIONS: This study showed an improvement of HRQOL in haemodialysis patients over an 11-year period of time, independent of global changes in the general population.
Databáze: OpenAIRE