Pla a 2 and Pla a 3 reactivities identify plane tree-allergic patients with respiratory symptoms or food allergy
| Autor: | M. Giani, Damiano Abeni, E. C. Guerra, Lorenzo Cecchi, Riccardo Asero, Enrico Scala, L. Pirrotta, Maria Locanto |
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| Rok vydání: | 2017 |
| Předmět: |
Adult
Male medicine.medical_specialty Adolescent Immunology Immunoglobulin E Gastroenterology Trees Diagnosis Differential Young Adult 03 medical and health sciences 0302 clinical medicine Food allergy Internal medicine Hypersensitivity Odds Ratio medicine Humans Immunology and Allergy Respiratory system Child Aged Aged 80 and over 030201 allergy biology business.industry Incidence (epidemiology) Infant Allergens Antigens Plant Middle Aged medicine.disease Tracheophyta Systemic reaction 030228 respiratory system Biochemistry Child Preschool biology.protein Female Symptom Assessment business Food Hypersensitivity |
| Zdroj: | Allergy. 72:671-674 |
| ISSN: | 0105-4538 |
| DOI: | 10.1111/all.13121 |
| Popis: | Nine hundred and thirty-nine rPla a 1, nPla a 2, and rPla a 3 ImmunoCAP ISAC reactors were studied. nPla a 2pos MUXF3pos but Pla a 1/2neg subjects were excluded from the study because they were cross-reactive carbohydrate determinant reactors. Among the 764 remaining participants, 71.9% were Pla a 3pos, 54.1% Pla a 2pos, and 10.9% Pla a 1pos. Among Pla a 3 reactors, 89.6% were Pru p 3pos and 86.8% Jug 3pos, but the strongest IgE recognition relationship was observed between Pla a 3 and Jug r 3. Distinctive clinical subsets could be documented among plane tree-allergic patients. Pla a 3 reactors had both local and systemic food-induced reactions, but lower past respiratory symptoms occurrence. Pla a 2 reactivity was associated with respiratory symptoms but inversely related to systemic reactions to food. Cosensitization to Pla a 2 and Pla a 3 was associated with a lower past incidence of severe food-induced reactions. |
| Databáze: | OpenAIRE |
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