Assessing the atrial electromechanical coupling during atrial focal tachycardia, flutter, and fibrillation using electromechanical wave imaging in humans
| Autor: | Alok Gambhir, Elaine Wan, Alexandre Costet, Elisa E. Konofagou, William Whang, Hasan Garan, Jean Provost |
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| Rok vydání: | 2015 |
| Předmět: |
Adult
Male Tachycardia Ectopic Atrial Tachycardia medicine.medical_specialty Heartbeat medicine.medical_treatment Health Informatics Article Internal medicine Atrial Fibrillation medicine Humans cardiovascular diseases Ultrasonography Fibrillation business.industry P wave Atrial fibrillation Ablation medicine.disease Myocardial Contraction Computer Science Applications Atrial Flutter cardiovascular system Cardiology Flutter Female medicine.symptom Electrophysiologic Techniques Cardiac business Atrial flutter |
| Zdroj: | Computers in Biology and Medicine. 65:161-167 |
| ISSN: | 0010-4825 |
| DOI: | 10.1016/j.compbiomed.2015.08.005 |
| Popis: | Minimally-invasive treatments of cardiac arrhythmias such as radio-frequency ablation are gradually gaining in importance in clinical practice but still lack a noninvasive imaging modality which provides insight into the source or focus of an arrhythmia. Cardiac deformations imaged at high temporal and spatial resolution can be used to elucidate the electrical activation sequence in normal and paced human subjects non-invasively and could potentially aid to better plan and monitor ablation-based arrhythmia treatments. In this study, a novel ultrasound-based method is presented that can be used to quantitatively characterize focal and reentrant arrhythmias. Spatio-temporal maps of the full-view of the atrial and ventricular mechanics were obtained in a single heartbeat, revealing with otherwise unobtainable detail the electromechanical patterns of atrial flutter, fibrillation, and tachycardia in humans. During focal arrhythmias such as premature ventricular complex and focal atrial tachycardia, the previously developed electromechanical wave imaging methodology is hereby shown capable of identifying the location of the focal zone and the subsequent propagation of cardiac activation. During reentrant arrhythmias such as atrial flutter and fibrillation, Fourier analysis of the strains revealed highly correlated mechanical and electrical cycle lengths and propagation patterns. High frame rate ultrasound imaging of the heart can be used non-invasively and in real time, to characterize the lesser-known mechanical aspects of atrial and ventricular arrhythmias, also potentially assisting treatment planning for intraoperative and longitudinal monitoring of arrhythmias. |
| Databáze: | OpenAIRE |
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