| Popis: |
Lead is one of the heavy metal humans are often expose to either through food, cosmetics or environment. This study is aimed at investigating the positive effect ofSolanum melongena (garden egg), Solanum lycopersicum (tomatoes) and Daucus carrots subsp.sativus(carrot) on blood glucose concentration, body weight, and feeding habits of albino rats on lead toxicity. In this study 35 albino rats weighing 80-120g were grouped into five. Group 1 served as normal control, group 2 negative control. The remaining three groups served as treatment groups 1, 2 and 3. All groups except group 1 (normal control) were administered 50mg/kg of lead acetate. Treatment groups were administered 200mg/kg ofSolanum melongena (garden egg), Solanum lycopersicum (tomatoes) and Daucus carrots subsp.sativus(carrot). Group 3 was administeredSolanum malongenandDaucus carrots subsp.sativuswhile group 4 was givenDaucuscarrots subsp.sativusandsolanum lycopersicon. Group 5 was administeredSolanum malongen, Daucus carrots subsp.sativusandSolanum lycopersicon. Changes in blood glucose concentration, body weight, feed and water consumption recorded at intervals. The result showed a significant decrease (P0.05, P>0.01 and P>0.001) in body weight and feed consumed in treatment groups compared to negative control. Combined therapy of any two ofSolanum malongen,Daucus carrots subsp.sativusandSolanum lycopersiconjuice can help in the management of hyperglycemia and reverse internal abnormality or injury resulting in weight loss in lead induced toxicity. |
