Mechanical, Histological, and Scanning Electron Microscopy Study of the Effect of Mixed-Acid and Heat Treatment on Additive-Manufactured Titanium Plates on Bonding to the Bone Surface

Autor: Shinpei Maruyama, Phuc Thi Minh Le, Kayoko Yamamoto, Tomiharu Matsushita, Ayako Ochi, Keisuke Matsumoto, Hiroyuki Nakano, Seiji Yamaguchi, Nahoko Kato-Kogoe, Yoichiro Nakajima, Takaaki Ueno, Naoko Imagawa, Kazuya Inoue, Michi Omori
Rok vydání: 2020
Předmět:
Materials science
chemistry.chemical_element
custom-made plate
02 engineering and technology
lcsh:Technology
Article
law.invention
03 medical and health sciences
0302 clinical medicine
law
medicine
bone bonding
General Materials Science
Mechanical Evaluation
Bone formation
titanium
Selective laser melting
lcsh:Microscopy
Scanning electron microscopy study
lcsh:QC120-168.85
mixed-acid and heat treatment
lcsh:QH201-278.5
lcsh:T
030206 dentistry
021001 nanoscience & nanotechnology
medicine.anatomical_structure
chemistry
lcsh:TA1-2040
selective laser melting
Cortical bone
lcsh:Descriptive and experimental mechanics
lcsh:Electrical engineering. Electronics. Nuclear engineering
Electron microscope
0210 nano-technology
lcsh:Engineering (General). Civil engineering (General)
lcsh:TK1-9971
additive manufacturing
Bone surface
Biomedical engineering
Titanium
Zdroj: Materials
Materials, Vol 13, Iss 5104, p 5104 (2020)
Volume 13
Issue 22
ISSN: 1996-1944
Popis: The additive manufacturing (AM) technique has attracted attention as one of the fully customizable medical material technologies. In addition, the development of new surface treatments has been investigated to improve the osteogenic ability of the AM titanium (Ti) plate. The purpose of this study was to evaluate the osteogenic activity of the AM Ti with mixed-acid and heat (MAH) treatment. Fully customized AM Ti plates were created with a curvature suitable for rat calvarial bone, and they were examined in a group implanted with the MAH-treated Ti in comparison with the untreated (UN) group. The AM Ti plates were fixed to the surface of rat calvarial bone, followed by extraction of the calvarial bone 1, 4, 8, and 12 weeks after implantation. The bonding between the bone and Ti was evaluated mechanically. In addition, AM Ti plates removed from the bone were examined histologically by electron microscopy and Villanueva&ndash
Goldner stain. The mechanical evaluation showed significantly stronger bone-bonding in the MAH group than in the UN group. In addition, active bone formation was seen histologically in the MAH group. Therefore, these findings indicate that MAH resulted in rapid and strong bonding between cortical bone and Ti.
Databáze: OpenAIRE
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