The effects of midazolam administered postoperatively on emergence agitation in pediatric strabismus surgery
| Autor: | Eui-Tai Lee, Jin Ho Bae, Seon-jung Kim, Dong Hun Lee, Chang-jin Kang, Bon Wook Koo |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2010 |
| Předmět: |
Clinical Research Article
medicine.medical_specialty genetic structures business.industry sevoflurane emergence agitation Sevoflurane Surgery lcsh:RD78.3-87.3 Anesthesiology and Pain Medicine midazolam lcsh:Anesthesiology Anesthesia medicine Midazolam heterocyclic compounds business medicine.drug Strabismus surgery Recovery phase Sevoflurane anesthesia |
| Zdroj: | Korean Journal of Anesthesiology, Vol 58, Iss 1, Pp 45-49 (2010) Korean Journal of Anesthesiology |
| ISSN: | 2005-7563 2005-6419 |
| Popis: | Background The present study tested the effect of midazolam administration after sevoflurane anesthesia against emergence agitation in children in the recovery phase. Methods A total of 60 children presenting for ophthalmic surgery under sevoflurane anesthesia were randomly placed in four groups from Group I to Group IV. Before the end of the surgery, we injected normal saline 2 ml in Group I and Group IV. We administered a 2-ml mixture of midazolam 0.025 mg/kg and midazolam 0.050 mg/kg to Group II and Group III respectively. Among the patients with agitation scores 4 or 5 in the peostanesthesia care unit (PACU), Group IV patients were intravenously given a 1-ml mixture of midazolam 0.025 mg/kg and normal saline up to 3 times. Agitation parameters, anesthesia recovery times, and the total administration amounts of midazolam were measured. Results Extubation time was significantly longer and maximum agitation scores higher in Group III than in Group I. The rate of the length of the period when the agitation score was 4 or 5 out of the length of stay in the PACU was significantly lower in Group II, Group III, and Group IV than in Group I. The length of stay in the PACU was significantly longer in Group III, and Group IV than in Group I. Conclusions For pediatric patients under sevoflurane anesthesia, postoperative midazolam administration slightly prolonged the length of stay in the PACU. But it effectively reduced emergence agitation without any side effects. |
| Databáze: | OpenAIRE |
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