The Role of the Anaphase-Promoting Complex/Cyclosome in Plant Growth
| Autor: | Marcelo de Freitas Lima, Nubia Barbosa Eloy, Paulo Cg Ferreira, Dirk Inzé |
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| Rok vydání: | 2015 |
| Předmět: |
F-BOX PROTEINS
Arabidopsis Plant Science F-box protein ubiquitin-ligase APC/C activator protein CDH1 SACCHAROMYCES-CEREVISIAE Cyclin-dependent kinase CDK INHIBITORS CELL-CYCLE APC/C UBIQUITIN LIGASE Cell division control protein 4 Mitosis ENDOCYCLE ONSET SISTER-CHROMATID SEPARATION biology Biology and Life Sciences CYCLIN-DEPENDENT KINASE Cell cycle Ubiquitin ligase Cell biology MEIOSIS-II TRANSITION ARABIDOPSIS-THALIANA biology.protein cell cycle plant development Anaphase-promoting complex |
| Zdroj: | CRITICAL REVIEWS IN PLANT SCIENCES |
| ISSN: | 1549-7836 0735-2689 |
| DOI: | 10.1080/07352689.2015.1078613 |
| Popis: | The anaphase-promoting complex/cyclosome (APC/C) is a multi-subunit E3 ubiquitin ligase that plays a major role in the progression of the eukaryotic cell cycle. This unusual protein complex targets key cell cycle regulators, such as mitotic cyclins and securins, for degradation via the 26S proteasome by ubiquitination, triggering the metaphase-to-anaphase transition and exit from mitosis. Because of its essential role in cell cycle regulation, the APC/C has been extensively studied in mammals and yeasts, but relatively less in plants. Evidence shows that, besides its well-known role in cell cycle regulation, the APC/C also has functions beyond the cell cycle. In metazoans, the APC/C has been implicated in cell differentiation, disease control, basic metabolism and neuronal survival. Recent studies also have shed light on specific functions of the APC/C during plant development. Plant APC/C subunits and activators have been reported to play a role in cellular differentiation, vascular development, shoot branching, female and male gametophyte development and embryogenesis. Here, we discuss our current understanding of the APC/C controlling plant growth. |
| Databáze: | OpenAIRE |
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