Additional value of thallium-201 SPECT to a conventional exercise test for the identification of severe coronary lesions after an episode of unstable coronary artery disease
| Autor: | Eva Nylander, Anders Björkholm, Lars Wallentin, Jan Ohlsson, Jan Erik Karlsson |
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| Rok vydání: | 1995 |
| Předmět: |
Adult
Male Coronary angiography medicine.medical_specialty chemistry.chemical_element Coronary Disease Coronary Angiography Sensitivity and Specificity Coronary artery disease Electrocardiography Double-Blind Method Predictive Value of Tests Internal medicine THREE VESSEL DISEASE medicine Humans Radiology Nuclear Medicine and imaging Prospective Studies Depression (differential diagnoses) Cardiac imaging Aged Sweden Tomography Emission-Computed Single-Photon medicine.diagnostic_test business.industry Heart Middle Aged medicine.disease Thallium Radioisotopes Stenosis Logistic Models chemistry Tissue Plasminogen Activator Angiography Exercise Test Cardiology Thallium Radiology Cardiology and Cardiovascular Medicine business |
| Zdroj: | The International Journal of Cardiac Imaging. 11:127-137 |
| ISSN: | 1573-0743 0167-9899 |
| DOI: | 10.1007/bf01844710 |
| Popis: | The additional value of thallium-201 SPECT to a conventional exercise test for the identification of patients with severe coronary lesions was evaluated in 170 men, one month after an episode of unstable coronary artery disease. Severe coronary lesions at coronary angiography--defined as three vessel disease, left main stenosis or proximal left anterior descending artery stenosis as part of two vessel disease--were observed in 45.9%. In the SPECT image, the left ventricular myocardium was divided into nine segments and each segment was classified as either normal (= 0), reduced uptake (= 1) or uptake defect (= 2). The sum of gradings in all segments post-exercise was denoted "SPECT score". The patients were divided into nine different groups regarding ST-depression during exercise (no ST-depression, ST-depression in 1-2 leads oror = 3 leads) and "SPECT score" (no SPECT score, 1-3 scores oror = 4 scores). Severe coronary lesions were, in 68% identified by SPECT scoreor = 4 and in 65% by ST-depression inor = 1 lead at exercise test. The specificity for identification of severe coronary lesions was, for both tests, 65%. SPECT scoreor = 4 and/or ST-depression inor = 3 leads identified 82% of the patients with severe coronary lesions with a specificity of 63%. Furthermore, SPECT scoreor = 3 identified more patients with isolated proximal left anterior descending artery stenosis than ST-depression alone at exercise test. |
| Databáze: | OpenAIRE |
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