Selective acetolysis of primary benzyl groups in carbohydrate derivatives under the mild reaction condition
| Autor: | Monalisa Kundu, Anup Kumar Misra |
|---|---|
| Rok vydání: | 2019 |
| Předmět: |
Perchlorates
Primary (chemistry) 010405 organic chemistry Chemistry Organic Chemistry Acetic Anhydrides Carbohydrates General Medicine Solid acid Carbohydrate Silicon Dioxide 010402 general chemistry 01 natural sciences Biochemistry Catalysis 0104 chemical sciences Analytical Chemistry Kinetics Acetic anhydride chemistry.chemical_compound Acetylation Yield (chemistry) Organic chemistry Perchloric acid |
| Zdroj: | Carbohydrate Research. 486:107830 |
| ISSN: | 0008-6215 |
| DOI: | 10.1016/j.carres.2019.107830 |
| Popis: | Selective acetolysis of the primary benzyloxy groups in a wide variety of carbohydrate derivatives was achieved in excellent yield using acetic anhydride and perchloric acid supported over silica (HClO4–SiO2) as a solid acid catalyst in a fast reaction condition without using any organic solvent. The reaction condition is significantly rapid and can be scaled up for its use in the multi-step oligosaccharide synthesis. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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