Surgical Repair of Ventricular Septal Defect; Contemporary Results and Risk Factors for a Complicated Course

Autor: Maartje Schipper, Johannes M.P.J. Breur, Paul H. Schoof, Martijn G. Slieker
Jazyk: angličtina
Rok vydání: 2016
Předmět:
Heart Septal Defects
Ventricular
Male
Multivariate analysis
Time Factors
030204 cardiovascular system & hematology
Ventricular septal defect
Pediatrics
0302 clinical medicine
Postoperative Complications
Risk Factors
Child
Netherlands
Pediatric cardiac surgery
Cardiac surgery
Treatment Outcome
Child
Preschool
Cardiology
Original Article
Female
Cardiology and Cardiovascular Medicine
Reoperation
medicine.medical_specialty
Adolescent
Heart block
Pediatric cardiology
03 medical and health sciences
Intensive care
Internal medicine
medicine
Humans
Pediatrics
Perinatology
and Child Health
Risk factor
Cardiac Surgical Procedures
Adverse effect
Congenital heart disease
Retrospective Studies
Surgical repair
business.industry
Other Research Radboud Institute for Health Sciences [Radboudumc 0]
Infant
Newborn
Infant
Vascular surgery
medicine.disease
Surgery
Heart Block
Logistic Models
030228 respiratory system
Pediatrics
Perinatology and Child Health
Multivariate Analysis
business
Zdroj: Pediatric Cardiology
Pediatric Cardiology, 38, 2, pp. 264-270
Pediatric Cardiology, 38, 264-270
ISSN: 1432-1971
0172-0643
Popis: Contains fulltext : 170596.pdf (Publisher’s version ) (Open Access) Surgical closure of the ventricular septal defect is the most commonly performed procedure in pediatric cardiac surgery. There are conflicting data on weight at operation as risk factor for a complicated course. We performed a retrospective evaluation of mortality and morbidity in all patients undergoing surgical ventricular septal defect closure at our institution between 2004 and 2012 to identify risk factor for a complicated course. Multivariate logistic regression modeling was performed to identify risk factors for a complicated course. 243 patients who underwent surgical ventricular septal defect closure were included. Median age at operation was 168.0 days (range 17-6898), the median weight 6.0 kg (range 2.1-102.0). No deaths occurred. Two patients (0.8%) required a pacemaker for permanent heart block. Five patients (2.1%) underwent reoperation for a hemodynamically important residual ventricular septal defect. No other major adverse events occurred. No risk factors for major adverse events could be established. Multivariate analysis identified a genetic syndrome, long bypass time and low weight at operation as independent risk factors for a prolonged intensive care stay (>1 day) and prolonged ventilation time (>6 h). Contemporary results of surgical VSD closure are excellent with no mortality and low morbidity in this series. Although it is associated with increased ventilation time and a longer hospital stay, low bodyweight at operation is not associated with an increased risk of complications or major adverse events in our series.
Databáze: OpenAIRE
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