Simultaneous supercritical fluid extraction of heather (Calluna vulgaris L.) and marigold (Calendula officinalis L.) and anti-inflammatory activity of the extracts
| Autor: | Erika Vázquez, Susana Santoyo, Mónica Rodríguez García-Risco, Marisol Villalva, David Villanueva-Bermejo, Tiziana Fornari, Guillermo Reglero |
|---|---|
| Přispěvatelé: | UAM. Departamento de Química Física Aplicada, Ministerio de Economía y Competitividad (España), Comunidad de Madrid, Villalva, Marisol, Villalva, Marisol [0000-0002-2366-7268] |
| Rok vydání: | 2019 |
| Předmět: |
02 engineering and technology
01 natural sciences lcsh:Technology Supercritical fluid extraction Terpene lcsh:Chemistry chemistry.chemical_compound Triterpene General Materials Science Instrumentation lcsh:QH301-705.5 ComputingMilieux_MISCELLANEOUS anti-inflammatory Fluid Flow and Transfer Processes chemistry.chemical_classification Supercritical carbon dioxide biology General Engineering Triterpenic acids Química lcsh:QC1-999 Computer Science Applications Fractionation combined extraction 020401 chemical engineering Ursolic acid 0204 chemical engineering Chromatography 010405 organic chemistry lcsh:T Process Chemistry and Technology Heather Extraction (chemistry) biology.organism_classification 0104 chemical sciences chemistry lcsh:Biology (General) lcsh:QD1-999 Calendula officinalis lcsh:TA1-2040 triterpenic acids supercritical fluid extraction marigold Anti-inflammatory lcsh:Engineering (General). Civil engineering (General) heather Marigold lcsh:Physics Combined extraction |
| Zdroj: | Biblos-e Archivo. Repositorio Institucional de la UAM Consejo Superior de Investigaciones Científicas (CSIC) Applied Sciences Volume 9 Issue 11 Applied Sciences, Vol 9, Iss 11, p 2245 (2019) Biblos-e Archivo: Repositorio Institucional de la UAM Universidad Autónoma de Madrid Digital.CSIC. Repositorio Institucional del CSIC instname |
| ISSN: | 2013-4894 |
| Popis: | This article belongs to the Special Issue Advances in Supercritical Fluid Food Science and Technology. Heather (Calluna vulgaris L.) and marigold (Calendula officinalis L.) are two rich sources of bioactive pentacyclic triterpenes. The supercritical carbon dioxide (SCCO2) extraction of these two plants was explored at a pressure range of 25–50 MPa, 50 °C, with or without fractionation, different extraction times (1.5–4.0 h) and using ethanol as a co-solvent (0 and 10% w/w). In order to determine potential synergisms, a combined extraction (heather + marigold 50:50) was also studied. In general, higher extraction yields were achieved when the co-solvent was added. Higher concentrations of total triterpenic acids were obtained in heather extracts, specially using ethanol. The co-solvent did not increase the terpene concentration in marigold extracts. For the combined extraction, an antagonist effect in the triterpene concentration was observed in absence of a co-solvent, whereas a synergistic effect was exhibited in its presence, especially for ursolic acid. In general, the extracts showed a certain anti-inflammatory effect, although a straight correlation with the analyzed triterpenic acids concentration was not exhibited. Moreover, the combined extraction exposed a similar anti-inflammatory activity in comparison with the individual plant extracts. The authors gratefully acknowledge the financial support from Ministerio de Economía y Competitividad of Spain (project AGL2013-48943-C2) and the Comunidad Autónoma de Madrid (ALIBIRD, project number S2013/ABI-2728). |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|