Procedures for high precision setup verification and correction of lung cancer patients using CT-simulation and digitally reconstructed radiographs (DRR)
| Autor: | John R. van Soernsen de Koste, Regine H. Schuchhard-Schipper, Ben J.M. Heijmen, Suresh Senan, Hans C.J. de Boer |
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| Přispěvatelé: | Radiation Oncology, CCA - Cancer biology and immunology, CCA - Cancer Treatment and quality of life |
| Jazyk: | angličtina |
| Rok vydání: | 2003 |
| Předmět: |
Cancer Research
medicine.medical_specialty Lung Neoplasms Esophageal Neoplasms Radiography Treatment unit SDG 3 - Good Health and Well-being Carcinoma Non-Small-Cell Lung medicine Humans Radiology Nuclear Medicine and imaging Medical physics Computer vision In patient Ct simulation Skin marks Carcinoma Small Cell Radiation business.industry Radiotherapy Planning Computer-Assisted Isocenter Reproducibility of Results Oncology Digitally reconstructed radiographs Tomography Artificial intelligence business |
| Zdroj: | International Journal of Radiation Oncology Biology Physics, 55(3), 804-810. Elsevier Inc. Van Sörnsen De Koste, J R, De Boer, H C J, Schuchhard-Schipper, R H, Senan, S & Heijmen, B J M 2003, ' Procedures for high precision setup verification and correction of lung cancer patients using CT-simulation and digitally reconstructed radiographs (DRR) ', International Journal of Radiation Oncology Biology Physics, vol. 55, no. 3, pp. 804-810 . https://doi.org/10.1016/S0360-3016(02)04285-2 |
| ISSN: | 0360-3016 |
| DOI: | 10.1016/s0360-3016(02)04285-2 |
| Popis: | Purpose: In a recent study, large systematic setup errors were detected in patients with lung cancer when a conventional simulation procedure was used to define and mark the treatment isocenter. In the present study, we describe a procedure to omit the session at a conventional simulator to remove simulation errors entirely. Isocenter definition and verification was performed at a computed tomography (CT) simulator, and digitally reconstructed radiographs (DRRs) were used for setup verification and correction at the treatment unit. Methods and Materials: A CT simulation protocol was developed, in which radiopaque markers were used to verify the coincidence of the isocenter marked on the patients' skin with the isocenter defined in the planning CT scan. This protocol was evaluated for 20 patients. Subsequently, electronic portal images were acquired at the treatment unit. The three-dimensional setup error was established from a template match of the appropriate anatomy visible in two orthogonal beams with the corresponding anatomy in DRRs. An offline setup correction protocol was applied to reduce systematic setup errors. Results: For all patients, the skin marks defined the planning CT scan isocenter to within ± 1.5 mm in each of the three main directions. Random setup errors at the treatment unit were 1.8, 2.0, and 1.9 mm (1 SD) for the lateral (x), the superior-inferior (y), and the anterior-posterior (z) directions, respectively. With the use of the correction protocol, the systematic errors for x, y, and z were 1.5, 1.5, and 1.3 mm (1 SD). Conclusions: Because the distributions of treatment setup errors measured against DRRs obtained in our CT simulation were equal to previously obtained distributions measured against simulator films, conventional simulation can be omitted and DRRs are well-suited for setup verification. By adopting our CT simulation procedure, the large systematic simulation setup errors, which remain hidden if a conventional simulation is performed, can be avoided. |
| Databáze: | OpenAIRE |
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