Passive immunity in newborn from SARS-CoV-2-infected mother
| Autor: | Laura Marchi, Pier Luigi Vasarri, Tamara Brunelli, D. Aquilini, Anna Franca Cavaliere |
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| Rok vydání: | 2020 |
| Předmět: |
Adult
Male Offspring viruses medicine.medical_treatment Passive immunity Antibodies Viral Immunoglobulin G 03 medical and health sciences 0302 clinical medicine Pregnancy Virology Medicine Humans 030212 general & internal medicine Pregnancy Complications Infectious Fetus biology Transmission (medicine) business.industry SARS-CoV-2 Infant Newborn Transplacental COVID-19 medicine.disease Infectious Disease Transmission Vertical Infectious Diseases Immunoglobulin M biology.protein 030211 gastroenterology & hepatology Female Antibody business Immunity Maternally-Acquired |
| Zdroj: | Journal of Medical Virology |
| ISSN: | 1096-9071 |
| Popis: | Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) vertical transmission is an open issue. Recent reports call into question in utero or peripartum viral transmission to the offspring. Few data are available on immunoglobulin G (IgG) and/or IgM in newborns. Insufficient evidence is available regarding passive immunity in neonates born from SARS-CoV-2 infected women. We report a case of a neonate showing the presence of blood specific IgG and the absence of IgM and negative nasopharyngeal swab. He was born from an asymptomatic SARS-CoV-2-infected mother with positive IgG and IgM. The transplacental passage of specific IgG antibodies from the affected mother to the unaffected fetus highlights neonatal passive immunity. |
| Databáze: | OpenAIRE |
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