Cognitive and physical performance are well preserved following standard blood donation: A noninferiority, randomized clinical trial
| Autor: | Ari M. Lipsky, Asher Moser, Nikolai Haiman, Roy Nadler, Eilat Shinar, Tarif Bader, Elon Glassberg, Jacob Chen, Ishai Ostffeld, Gadi Lending, Håkon S. Eliassen, Avi Benov, Ran Yanovich, Avishai M Tsur, Diana Levy |
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| Rok vydání: | 2020 |
| Předmět: |
Male
medicine.medical_specialty Randomization Blinding Immunology Vital signs Blood Donors Blood Pressure Physical exercise 030204 cardiovascular system & hematology law.invention Young Adult 03 medical and health sciences Cognition 0302 clinical medicine Double-Blind Method Randomized controlled trial Heart Rate law medicine Humans Immunology and Allergy Effects of sleep deprivation on cognitive performance Israel Exercise Blood type business.industry Hematology Physical Functional Performance Military Personnel Blood pressure Physical therapy business 030215 immunology |
| Zdroj: | Transfusion. 60 |
| ISSN: | 1537-2995 0041-1132 |
| Popis: | Background A walking blood bank (WBB) refers to the use of fellow combatants for battlefield blood donation. This requires pretesting combatants for infectious diseases and blood type. A fundamental prerequisite for this technique is that the donating soldier will suffer minimal physiological and mental impact. The purpose of the current study is to assess the effect of blood shedding on battlefield performance. Methods This is a double-blind randomized control trial. Forty Israel Defense Forces combatants volunteered for the study. Participants underwent baseline evaluation, including repeated measurement of vital signs, cognitive evaluation, physical evaluation, and a strenuous shooting test. Three weeks after the baseline evaluation, subjects were randomized to either blood donation or the control group. For blinding purposes, all subjects underwent venous catheterization for the duration of a blood donation. Repeated vital signs and function evaluation were then performed. Results Thirty-six patients were available for randomization. Baseline measurements were similar for both groups. Mean strenuous shooting score was 80.5 ± 9.5 for the control group and 82 ± 6.6 for the test group (p = 0.58). No clinically or statistically significant differences were found in tests designed to evaluate cognitive performance or physical functions. Vital signs taken multiple times were also similar between the test and control groups. Conclusions Executive, cognitive, and physical functions were well preserved after blood donation. This study supports the hypothesis that a WBB does not decrease donor combat performance. The categorical prohibition of physical exercise following blood donation might need to be reconsidered in both military and civilian populations. |
| Databáze: | OpenAIRE |
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