3-Formylindole-based chitosan Schiff base polymer: Antioxidant and in vitro cytotoxicity studies on THP-1 cells

Autor: M. Ameer Ali, Shazia Anjum Musthafa, Ganesh Munuswamy-Ramanujam, V. Jaisankar
Rok vydání: 2022
Předmět:
Zdroj: Carbohydrate Polymers. 290:119501
ISSN: 0144-8617
Popis: Two imine derivatives of chitosan (i-CTs), namely 2FCT and 5MCT, were synthesized by reacting chitosan (CT) with 2-(3-formyl-1H-indol-1yl)acetonitrile (2F), and 5-methoxyindole-3-carbaldehyde (5M), respectively. The antimicrobial evaluation of i-CTs exhibited stronger inhibition effect against Staphylococcus aureus, Escherichia coli and Candida albicans. The antioxidant activity of 2FCT and 5MCT showed strong scavenging ability with IC
Databáze: OpenAIRE