Mechanisms of Sensory Discrimination: Insights fromDrosophilaOlfaction
| Autor: | Gero Miesenböck, Lukas N. Groschner |
|---|---|
| Rok vydání: | 2019 |
| Předmět: |
Olfactory system
0303 health sciences biology Computer science Biophysics Probabilistic logic Bioengineering Cell Biology Olfaction biology.organism_classification Biochemistry 03 medical and health sciences 0302 clinical medicine Structural Biology Similarity (psychology) Biological neural network Neural coding Drosophila Neuroscience 030217 neurology & neurosurgery 030304 developmental biology Coding (social sciences) |
| Zdroj: | Annual Review of Biophysics. 48:209-229 |
| ISSN: | 1936-1238 1936-122X |
| DOI: | 10.1146/annurev-biophys-052118-115655 |
| Popis: | All an animal can do to infer the state of its environment is to observe the sensory-evoked activity of its own neurons. These inferences about the presence, quality, or similarity of objects are probabilistic and inform behavioral decisions that are often made in close to real time. Neural systems employ several strategies to facilitate sensory discrimination: Biophysical mechanisms separate the neuronal response distributions in coding space, compress their variances, and combine information from sequential observations. We review how these strategies are implemented in the olfactory system of the fruit fly. The emerging principles of odor discrimination likely apply to other neural circuits of similar architecture. |
| Databáze: | OpenAIRE |
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