The treatment with an extract from Calafate (Berberis microphylla) induces transcript and protein expression of molecules involved in thermogenesis and adipocyte browning in adipose tissue from obese mice
| Autor: | Vanessa Villanueva V, Javier Quezada, Francisco Pérez-Bravo, Luisa A. Ramirez, Juan Francisco Orellana, Lissette Duarte, Diego F. Garcia-Diaz, Karla Vasquez |
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| Rok vydání: | 2021 |
| Předmět: |
0301 basic medicine
medicine.medical_specialty Soil Science Adipose tissue 030209 endocrinology & metabolism Plant Science Horticulture Biochemistry Protein expression 03 medical and health sciences chemistry.chemical_compound 0302 clinical medicine Adipocyte Internal medicine medicine Browning Obese Mice 030109 nutrition & dietetics biology Chemistry Berberis microphylla biology.organism_classification Endocrinology Agronomy and Crop Science Thermogenesis Food Science |
| Zdroj: | Journal of Berry Research. 11:267-277 |
| ISSN: | 1878-5123 1878-5093 |
| DOI: | 10.3233/jbr-200670 |
| Popis: | BACKGROUND: Polyphenols intake increases the function of brown adipose tissue (BAT), stimulating energy expenditure (EE). Calafate (Berberis microphylla) is a polyphenol-rich Chilean native fruit. OBJECTIVE: To analyse the effect of a treatment with a Calafate extract in the thermogenic activity of mice adipose tissues. METHODS: Forty adult C57BL/6J male mice were subdivided into four groups (n=10 each): control diet, control+Calafate (extract: 50mg total polyphenols/kg weight), high-fat diet (HF) and HF+Calafate. RESULTS: Calafate prevented the increase in body weight and the decrease EE induced by HF. In BAT, Ucp-1 transcript was influenced by the interaction between diet and Calafate (p |
| Databáze: | OpenAIRE |
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