Dragon fruit extract capped gold nanoparticles: Synthesis and their differential cytotoxicity effect on breast cancer cells
| Autor: | Deepika Divakaran, Rohit Srivastava, Jaya R. Lakkakula, Mukesh Kumar Kumawat, Mukeshchand Thakur |
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| Rok vydání: | 2019 |
| Předmět: |
Materials science
medicine.diagnostic_test Mechanical Engineering 02 engineering and technology 010402 general chemistry 021001 nanoscience & nanotechnology Condensed Matter Physics 01 natural sciences 0104 chemical sciences chemistry.chemical_compound Biosynthesis chemistry Mechanics of Materials Transmission electron microscopy Colloidal gold Spectrophotometry medicine General Materials Science Breast cancer cells Growth inhibition 0210 nano-technology Cytotoxicity Nuclear chemistry |
| Zdroj: | Materials Letters. 236:498-502 |
| ISSN: | 0167-577X |
| DOI: | 10.1016/j.matlet.2018.10.156 |
| Popis: | Biosynthesis of gold nanoparticles from Dragon fruit extract (DF extract) can be considered as an eco-friendly alternative for synthesis of gold nanoparticles. The aim of this study was to investigate the ability of this fruit to synthesize gold nanoparticles and to study its anticancer activity. The as synthesized gold nanoparticles were characterized by UV-vis spectrophotometry, X-ray diffraction, Fourier Transform Infra-red spectroscopy and Transmission Electron microscopy. The results from XRD and TEM support the biosynthesis of DF extract capped gold nanoparticles (DF-AuNPs) in the size range of 10–20 nm. The DF extract and DF-AuNPs induced significant growth inhibition of MCF-7 breast cancer cells however, no significant toxicity effect was observed on MDA-MB-231 cells. |
| Databáze: | OpenAIRE |
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