A thermally polarized 129Xenon phantom for MR elastography studies in a ultra-high field MRI system
| Autor: | Irene Canavesi, Weiguo Li, Dieter Klatt, Thomas Royston |
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| Rok vydání: | 2023 |
| Předmět: | |
| Zdroj: | The Journal of the Acoustical Society of America. 153:A266-A266 |
| ISSN: | 1520-8524 0001-4966 |
| DOI: | 10.1121/10.0018803 |
| Popis: | Being second only to cardiovascular problems, respiratory diseases account for five of the 30 most common causes of death worldwide. One way to address this problem is by improving early diagnostic methods. Due to the complex heterogeneous structure of the lung, conventional imaging and elastography techniques based on ultrasound and magnetic resonance (MR) imaging have been limited in their ability to provide regional detail of morphology and mechanical properties, both of which can be altered by respiratory diseases. Hyperpolarized 129Xe(non) MR imaging has shown promise as a means of regionally quantifying ventilation, microstructure, and gas exchange efficiency in the lung parenchymae. MR elastography of the lungs using hyperpolarized gases is also being explored. To advance development, a stable phantom for MR imaging and elastography calibration using 129Xe is needed. The design, fabrication, and experimental testing of a stable thermally polarized 129Xe MR imaging and elastography phantom for a 9.4 T preclinical MR imaging system are presented. |
| Databáze: | OpenAIRE |
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