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Purpose: to establish the reliability of diagnostic markers and determine a change in the metabolic status in Novostic sick cows with acute purulent-catarrhal inflammation of the uterus.Materials and methods. Under the supervision were 2758 lactating cows. The clinical diagnosis of purulent-cataral metritis at the first-and-and-out cows in the early postpartum period was carried out as part of the obstetric and gynecological dispensation. Samples of blood for hematological studies were selected from cows before the morning meal, when confirming the diagnosis, acute purulent-catarrhal methy (n = 15), it was possible to study the “acid-abbreal state” systems (braids) and “lipid oxidation-antioxidant protection” (gender ”(gender -Aoz). During the analysis, the voltage in the blood of oxygen, carbon dioxide, buffer of blood, primary products of lipid peroxidation - the estimate was carried out according to the concentration of cdist and recreation center, isolated double bonds and ketodene. In the diagnosis of acute purulent-catarrhal inflammation of the former engraving horn of the uterus, from the 3rd to 10th day after the hotel at the Novotniki cows, which degree of the cervix was covered and the excudate is allocated from the genitals.Results. Acute inflammation of the uterus on the 9th ... 14th day after calving on echograms has a more pronounced cavity, which is increased by 1.72 times in comparison with echograms obtained from clinically healthy animals of the same study period, and the thickness of the uterine wall is increased by 1.71 times than in healthy animals and averaged 28.2 ± 0.6 mm. On echograms of the uterus, when scanning a sick animal with acute postpartum metritis, the cavity is identified with a diameter of 67.8 ± 4.6 mm, filled with purulent-catarrhal exudate with echopositive inclusions of medium and high density. In the field of view of the microscope on histopreparations, we clearly record the peeling of the epithelium by layers. Cellular infiltration of the endometrial and myometrial lamina is expressed. There are many plasma cells among the infiltrate cells. The mesothelium is preserved. Laboratory studies of blood samples obtained from sick cows revealed a shift in the content of buffer bases to 18.41 ± 1.53 mmol /l, a decrease to 2.25 ± 0.16 mmol / l of glucose, which indicates deviations in the daily metabolism characteristic of metabolic disorders with symptoms of metritis on the 5th ... 10th day after calving. In case of cow disease with acute purulent-catarrhal inflammation of the former gravid horn of the uterus, an increase of 2.24 times in the amount of malondialdehyde, 1.75 times in the intermediate products of ketodienes, as well as conjugated trienes in the blood plasma of new-bodied animals was confirmed. At the beginning of lactation, in the first ten days of the postpartum period, there is a decrease in the level of total protein and the fraction of γ - globulins in sick animals with acute purulent-catarrhal inflammation of the uterus, which is compensated by high stabilization of the processes of formation and elimination of medium circulating immune complexes with high affinity of antibodies. |
