| Autor: |
Purnima D. Amin, Tarique Ali Meer, Ajay Kumar Sav |
| Rok vydání: |
2012 |
| Předmět: |
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| Zdroj: |
Journal of Applied Pharmacy. 4:103-108 |
| ISSN: |
1920-4159 |
| DOI: |
10.21065/19204159.4.103 |
| Popis: |
A novel liquisolid compact technique was used for soulbility enahncement of poorly water soluble drug carvedilol (CAR). CAR was dissolved in water miscible non volatile solvent and then adsorbed on a solid carrier which was later compacted with other excipient into a tablet. The tablets were characterized with respect to hardness, friability, disintegration and in-vitro dissolution profile. Effect of storage conditions on dissolution profile was also studied. DSC and XRD studies were done to confirm the physical state of CAR in the formulation. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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