| Popis: |
Purpose: To compare the incidence of partial and complete expulsion for different copper intrauterine device (IUD) shapes. Materials and methods: A secondary analysis of the ongoing, prospective, non-interventional European Active Surveillance Study on LCS12 - an IUD with a total amount of 13.5 mg levonorgestrel (EURAS-LCS12). Women with newly inserted IUDs were recruited in 10 European countries (Austria, Germany, Poland, Czech Republic, Spain, Italy, United Kingdom, France, Sweden, and Finland) via a network of approximately 1,200 health care professionals. We calculated the cumulative incidence, crude and adjusted hazard ratios for expulsion. Results: For this analysis, 27,822 copper IUD users from the EURAS-LCS12 study were considered. The most frequently used IUD shape was T or Y (73.7%), followed by chains (12.1%), Omega (10.5%), and balls (3.8%). Cox regression analysis regarding partial expulsions yielded an adjusted hazard ratio (HRadj) of 1.8 (95% CI, 1.3-2.4), 0.2 (95% CI, 0.2-0.4), and 2.9 (95% CI, 2.1-3.9) for Omega-shape, chain, and ball versus T/Y-shape, respectively. For complete expulsions, HRadj was 0.5 (95% CI, 0.3-0.8), 1.7 (95% CI, 1.3-2.3) and 2.9 (95% CI, 2.0-4.2) for Omega-shape, chain and ball versus T/Y-shape, respectively. Conclusion: The shape of the copper IUD is associated with the risk of device expulsion and thus, should be considered at the time of contraceptive counseling. |
