| Popis: |
Summary The relapse of nasal polyps after surgical treatment remains a yet unsolved medical problem and, at the same time, a challenge for researchers. Starting from the observation that oedema, vessel dilatation and inflammatory cell infiltration are the histopathological characteristics of nasal polyps, our aim is to demonstrate the long-term efficacy of furosemide, administered by nasal inhalation, in preventing relapses of rhino-sinusal polyps after surgical treatment. In the study discussed in this paper, two groups of patients affected by rhino-sinusal polyposis were enrolled: 64 patients were included in the study group and 40 in the control group. After surgical treatment, the study group started the therapy with topic intranasal furosemide; the control group received no treatment. Six years after the operation only four cases of relapse were noticed in the study group (10%), while in the control group there were 12 relapses, four slight (6.4%) and eight severe (20%). Our paper concludes that local intranasal furosemide represents a valid therapeutic aid in the prevention of naso-sinusal polyps. |
