Cascade and RCM syntheses of chiral tricyclic alkaloids from (S)-1,2,3,4-tetrahydro isoquinoline carboxylic acid

Autor: Antonio Saba, Mauro Mucedda, Daniele Muroni
Rok vydání: 2009
Předmět:
Zdroj: Tetrahedron: Asymmetry. 20:1154-1159
ISSN: 0957-4166
DOI: 10.1016/j.tetasy.2009.04.003
Popis: Concise syntheses of novel chiral pyrroloazacyclo and chiral tricyclic isoquinoline alkaloids, starting from the readily available (S)-1,2,3,4-tetrahydroisoquinoline carboxylic acid methyl ester, by utilizing cascade spiro-to fused and RCM protocols, are reported.
Databáze: OpenAIRE