Blood Vessel Growth and Hypertrophic Scarring
| Autor: | SG Jones, Peter G. Shakespeare |
|---|---|
| Rok vydání: | 1992 |
| Předmět: |
Pathology
medicine.medical_specialty Cosmetic appearance Burn wound business.industry Dermatology Anatomy Fibrous tissue Pathology and Forensic Medicine Muscle hypertrophy medicine.anatomical_structure Dermis Hypertrophic scarring cardiovascular system Medicine Hypertrophic scars business Blood vessel |
| Zdroj: | Journal of Tissue Viability. 2:28-32 |
| ISSN: | 0965-206X |
| DOI: | 10.1016/s0965-206x(14)80043-0 |
| Popis: | Summary The technique of transcutaneous microscopy has been used to investigate blood vessel growth in hypertrophic scars. Hypertrophic scars were observed to contain large bore vessels with a dendritic pattern of growth. Many vessels grew from the edges of the original burn wound but few vessels appeared to grow from the base of the wound. The observations suggest that the degree of development of the scar is determined by the pattern of vessel growth. It is suggested that where the surface of the dermis is destroyed by the burn wound and subsequent healing processes, blood vessels may outgrow the boundaries normally imposed by a preserved dermis. It is also suggested that the volume of the fibrous tissue laid down in association with growing blood vessels is inversely proportional to the number of viable vessels remaining in the wound bed as start points for vessel growth. This proposal would explain the lack of hypertrophy observed under grafts and the cosmetic appearance of mesh grafted wounds. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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