Low prevalence ofKingella kingaecarriage in children aged 6-48 months in Sydney, Australia
| Autor: | Alison M. Kesson, Braden Rl Rivers, Alexander C. Outhred, Ameneh Khatami |
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| Rok vydání: | 2016 |
| Předmět: |
Pediatrics
medicine.medical_specialty biology business.industry Kingella kingae Kingella denitrificans medicine.disease_cause biology.organism_classification Throat swab Haemophilus influenzae 03 medical and health sciences 0302 clinical medicine Carriage Streptococcus agalactiae 030225 pediatrics Pediatrics Perinatology and Child Health Streptococcus pneumoniae Medicine 030212 general & internal medicine Flucloxacillin business medicine.drug |
| Zdroj: | Journal of Paediatrics and Child Health. 53:170-172 |
| ISSN: | 1034-4810 |
| Popis: | Aim A prospective observational study was conducted to estimate the prevalence of oropharyngeal carriage of Kingella kingae in healthy Australian pre-school children. Methods Screening for carriage of K. kingae as well as Streptococcus pyogenes, Streptococcus pneumoniae, Streptococcus agalactiae, Staphylococcus aureus, Haemophilus influenzae, and K. kingae was undertaken using a single bacterial throat swab taken from well children aged 6 months to 4 years. Standard laboratory procedures were used for culture and identification of organisms. Results One hundred children were enrolled between October and December 2014 at the Children's Hospital at Westmead. Median age was 24.0 months (range 6.1–48.8 months); 52 children were male and 36 attended day-care facilities. Forty-one children had siblings aged less than 5 years and 67 children had siblings of any age. K. kingae oropharyngeal carriage was not detected in any of the children. Rates of carriage of other organisms were: 30% S. aureus, 21% H. influenzae, 2% S. pneumoniae and 2% S. pyogenes. Thirty-eight children were colonised with Kingella denitrificans. Conclusions Our results suggest that prevalence of K. kingae carriage in pre-school children in Sydney is very low and support local and national guidelines that recommend flucloxacillin as empiric first-line therapy for children with osteoarticular infections. Studies conducted over the winter months and in other Australian centres could help answer outstanding questions regarding differences in carriage rates of K. kingae in children. |
| Databáze: | OpenAIRE |
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