The Role of the Vascular Factor in the Reorganization of Water Metabolism in Denervated Liver after Bacterial Endotoxin Poisoning

Autor: Tsibulevskiĭ AIu, Bykov Av, Gadziev KhK, Sergeev Ai, Dubovaia Tk, Shchegolev Ai
Rok vydání: 2005
Předmět:
Zdroj: Biology Bulletin. 32:590-596
ISSN: 1608-3059
1062-3590
Popis: Intoxication with bacterial lipopolysaccharide (endotoxin) is accompanied by considerable rearrangements in the systems of blood microcirculation and water metabolism of the liver. These rearrangements are manifested as increased sinusoid area, changed total area of the cytoplasm and nuclei as well as the nucleocytoplasmic ratio in hepatocytes, increased content of total water in the organ, and changed magnetic relaxation properties (spin-lattice and spin-spin relaxation times). Preliminary parasympathetic denervation of the liver (vagotomy) changes the pattern of the organ response to bacterial endotoxin poisoning as indicated by the kinetics of studied morphological and biophysical parameters.
Databáze: OpenAIRE